Professor Jeremy Guggenheim
Professor in Myopia Research
- guggenheimj1@cardiff.ac.uk
- +44 (0) 29 2087 4904
- Fax:
- +44 (0) 29 2087 4859
- 2.20, Maindy Road
- Available for postgraduate supervision
Overview
My research is aimed at discovering the causes of short-sightedness (myopia). Approximately 1 in 3 people in the United Kingdom suffer from myopia, and the condition increases the risk of a number of serious eye disorders. I have contributed to collaborative efforts with researchers from across the world, leading to the discovery of more than a hundred genetic variants that increase susceptibility to myopia.
Nobody yet knows how most of these genetic variants play a role in myopia development, nor how best they can be used to target and improve treatment.
Biography
Educational and Professional Qualifications
1989-1992: PhD, Cardiff University, UK
1988-1989: PQE (Optometry), British College of Optometrists
1985-1988: BSc (Hons) Optometry, UWIST (Cardiff University)
Career Overview
2013-2015 Assoc. Prof. & Assoc. Head, Optometry, Hong Kong Polytechnic University
2012-2013 Assoc. Prof., School of Optometry, Hong Kong Polytechnic University
2011-2012 Reader, School of Optometry & Vision Sciences, Cardiff University, UK
2006-2011 Senior Lecturer, School of Optometry & Vision Sciences, Cardiff University, UK
1994-2006 Lecturer, School of Optometry & Vision Sciences, Cardiff University, UK
Honours and awards
2012/2013 College of Optometrists, Biennial Arthur Bennett Prize for Outstanding Research Anywhere in the World
2022 Association for Research in Vision & Ophthalmology (ARVO) Gold Fellow Award
Professional memberships
1989 - present: Member of the College of Optometrists (MCOptom)
Academic positions
2013-2015 Assoc. Prof. & Assoc. Head, Optometry, Hong Kong Polytechnic University
2012-2013 Assoc. Prof., School of Optometry, Hong Kong Polytechnic University
2011-2012 Reader, School of Optometry & Vision Sciences, Cardiff University, UK
2006-2011 Senior Lecturer, School of Optometry & Vision Sciences, Cardiff University, UK
1994-2006 Lecturer, School of Optometry & Vision Sciences, Cardiff University, UK
Speaking engagements
Recent speaking engagements
Centro Oftalmologico Virgilio Galvis, Floridablanca, Colombia. 9 November 2021. “Recent developments in the genetics of myopia.”
Juzhou Symposium and international Myopia Conference, Chengdu, China. 27 October 2021. “Whole exome sequencing in 51,624 participants identifies novel genes and variants associated with myopia”.
Cardiff University Cornea-to-Cortex series. 24 March 2021. “Does education cause myopia?”
Manchester Optometry Meeting. 25 June 2021. Keynote Lecture: “Genetic prediction of myopia”
The Macular Society. Online Seminar. 30 July, 2020. “Current Myopia Research: from Bench to Kindergarten.”
Optometry Tomorrow, College of Optometrists. Telford, UK. 23-24 February, 2020. “Recent Developments in Myopia Research.”
UK Biobank Eye & Vision Consortium Annual Meeting 2020. Wellcome Trust, London. “Myopia Genetics Update.”
UK Biobank Eye & Vision Consortium Annual Meeting 2019. Wellcome Trust, London. “Evidence for widespread gene-environment interactions contributing to myopia.”
Ophthalmic Research Symposium, University of Tubingen Institute for Ophthalmic Research. 7 March, 2019. “The blurry line between genes and environment in causing myopia”.
19th DAKG Expertentagung & EurOK Congress, Hamburg, Germany. 20-21 October, 2018. “Epidemiology of myopia: Genetic and environmental risk factors.”
48th ECLSO (European Contact Lens Society of Ophthalmologists) congress, Mandelieu-La-Napoule, France. 14-15 September, 2018. “Epidemiology of myopia: Genetic and environmental risk factors.”
Committees and reviewing
University Committees
2015 - present: School Research Committee
2015 - present: School Research Audit Ethics Committee (Chair)
2017 - present: College Data Strategy Committee
Editorial Boards
2012 - present: Editorial Board Member, Ophthalmic & Physiological Optics (OPO)
2012 - present: Editorial Board Member, Translational Vision Science & Technology (TVST)
2023 - present: Associate Editor for Investigative Ophthalmology and Visual Science (IOVS)
Grant Panels
2020 - present: Fight for Sight UK grants assessment panel
Grant Reviewer
MRC, BBSRC, NIHR, Fight for Sight, Macular Society, College of Optometrists
Publications
We are currently unable to retrieve the list of publications. Visit our institutional repository.Teaching
Currently I am module leader for the Investigative Technqiues undergraduate course.
Research Topics and Related Projects
Translating myopia genetics discoveries into strategies for early detection and mechanistic insight
Collaborators: Dr Cathy Williams (University of Bristol, UK) and Professor Kyoko Ohno-Matsui (Tokyo Medical and
Dental University, Japan).
This study is funded jointly by the Welsh Assembly government and the eye research charity, Fight for Sight. It aims to discover if genetic information can help detect patients with high myopia who are at most risk of developing sight-threatening changes such as myopic maculopathy.
The Consortium for Refractive Error and Myopia (CREAM)
Collaborators: More than 30 teams of researchers from across the world.
The CREAM consortium carry out collaborative projects designed to identify genetic risk factors for refractive errors. Projects are co-ordinated by working groups, involving teams of researchers with expertise in genetics, biostatistics and ophthalmology. I co-Chair of the Astigmatism Working Group (with Joan Bailey-Wilson, NIH/NHGRI, USA) and the Longitudinal Studies Working Group (with Cathy Williams, Bristol, UK).
The UK Biobank Eye and Vision Consortium is a team of researchers working collaboratively to identify risk factors for eye diseases in the UK and to develop new treatments, by studying participants of UK Biobank.
Past Postgraduate Student (with degree and year submitted)
Michael Frost PhD 2000
Natalie Davies PhD 2002
Jane Farbrother PhD 2003
Carolina Chan PhD 2005
Rosalind Creer PhD 2006
Tetyana Zayats MD PhD 2009
Yen-Po (Paul) Chen MD PhD 2010
George McMahon PhD 2010
Chris Dillingham PhD 2012
Rupal Shah PhD 2018
Yvonne Huang Yu MD PhD 2018
Neema Ghorbani Mojarrad PhD 2020
Alfred Pozarickij PhD 2020
Denis Plotnikov MD PhD 2020